Altrenogest for Horses: Dosing, Side Effects, and Benefits for Reproductive Management

Managing your mare’s reproductive cycle has a variety of benefits, most notably improving their behaviors and contributing to the success of breeding programs. One of the most popular options for reproductive management is altrenogest for horses. This synthetic hormone helps regulate the estrous cycle, helping horse owners and veterinarians more effectively care for breeding mares.

What is Altrenogest for Horses?

Altrenogest mimics the natural hormone progesterone, which is vital in regulating the estrous cycle in mares and maintaining pregnancy. The estrous cycle, also referred to as the heat cycle, is the reproductive cycle of mares that lasts 21 days on average. It involves a series of physiological and behavioral changes that prepare mares for conception and pregnancy. 

By administering altrenogest for horses, veterinarians can help control this reproductive cycle, allowing for better management of breeding schedules and improved handling of behavior related to estrus. Estrus is the part of the reproductive cycle when the horse is in heat, usually lasting 5-7 days. This is the ideal time for breeding.

Understanding the Uses of Altrenogest for Horses

Altrenogest for horses manages the estrous cycle in mares by suppressing estrus, or when the mare is in heat. Doing this allows horse owners to synchronize breeding schedules. Synchronization is particularly important for large breeding operations. By knowing exactly when a mare is ovulating, horse owners can ensure breeding happens at the most optimal time—enhancing fertility rates and improving the chance of a successful pregnancy. Plus, it allows owners to plan when foals will be born.

Beyond the reproductive benefits, altrenogest for horses is also used to manage undesirable behavioral issues during estrus. These behaviors can include:

• Irritability: Mares may act more agitated or unsettled during estrus. They might paw at the ground, pace, or seem generally uneasy.
• More Vocalization: Mares may neigh or whinny more often to signal their readiness to potential mates.
• Frequent Urination: Mares in estrus often urinate more often, sometimes in small amounts, as a way to release pheromones and signal their reproductive status.
• Teasing: Mares may show more pronounced teasing behaviors toward stallions, including turning their hindquarters toward them or allowing them to nuzzle.
• Tail Raising: Mares might frequently raise their tails, which is another way to show that they’re receptive to mating.
• Increased Affection or Aggression: Some mares may become more affectionate toward humans and other horses, while others might show greater aggression or sensitivity.

Dosing and Administration Guidelines

Commercial altrenogest is typically given orally at a dose of 0.044 mg/kg once per day. The dosage can vary based on the specific needs of the horse and your veterinarian's recommendations. Oftentimes, it is necessary to customize altrenogest dosing to meet the unique needs of your mare. Compounding pharmacies, such as Mixlab, offer tailored formulations to ensure your horse receives the dosage they need. For example, it can be compounded into an easy-to-administer injectable. 

When prescribing altrenogest, veterinarians should consider the specific needs of the horse and the goals of the owner. Regular follow-up appointments and monitoring of the mare’s treatment response are an important part of the care plan.

Side Effects of Altrenogest for Horses

Altrenogest for horses is generally safe. There are no reported side effects when using altrenogest properly and according to the dosage instructions. Mild increases in liver enzymes are rarely seen. Veterinarians should monitor any of your mares on altrenogest to ensure they’re tolerating it well.

Additional Reproductive Management Solutions

Aside from altrenogest for horses, there are other reproductive management options for your mare. Some of these include:

• Prostaglandins: This option can be used to quickly put horses into heat, which is especially useful for mares who may have irregular cycles.
• Human Chorionic Gonadotropin (hCG): This hormone can be used to induce ovulation in mares.
• Progesterone/Estrogen: These hormones can be injected to suppress and control a mare’s reproductive cycle.

Addressing Misconceptions About Altrenogest for Horses

One common misconception is that altrenogest is only suitable for breeding mares. In reality, it is also effective in managing behavior and performance-related issues. By reducing the distractions and discomfort associated with estrus, mares can concentrate better on their tasks, improving their performance and safety during training and competition. Another myth is that altrenogest can cause long-term fertility problems, which is not supported by research when used appropriately under veterinary guidance.

Looking to Order Altrenogest for Horses? Mixlab Has You Covered.

Altrenogest is a powerful tool in equine reproductive management, offering significant benefits in breeding and behavior management. With a valid prescription from your veterinarian, you can easily order altrenogest for horses from Mixlab. We offer convenient, two-day delivery of your medication, along with custom compounding options to meet your mare’s unique needs. Get in touch with our team to place your order.